The Structure Group at NCBI just released new help files to help explain how to use the 3D Macromolecular Structure resources and Conserved Domains resources. Hats off to NCBI for more wonderful support materials!
Read more about the NCBI Structure Group, including research and publications, and learn how to discover associations among previously disparate data.
NCBI Structure Group efforts focus on four areas. Be sure to take a few minutes to browse through all of the wonderful resources offered by this group!
- Macromolecular structures
- Conserved domains and protein classification
- Small molecules and their biological activity
- Biological Systems
…and here are some “how to” files which might be particularly useful:
- Retrieve structures for a gene/protein product of interest
- Retrieve 3D structures bound to a specific chemical (e.g., aspirin)
- Align a query protein to a similar sequence from a 3D structure and interactively view sequence/structure relationships
- Identify the putative function of a protein sequence
- Identify the specific amino acids in a protein sequence that are putatively involved in functions such as binding or catalysis