The Human Genome Epidemiology Network (HuGENet™) is a voluntary, international collaboration focused on assessing the role of human genome variation in health and disease at the population level. Since 2001, HuGENet™ has maintained a database of published, population-based epidemiologic studies of human genes extracted and curated from PubMed. The HuGE Navigator replaces earlier search tools for use with this database and provides additional applications for use by researchers and the public.

HuGE Navigator provides access to a continuously updated knowledge base in human genome epidemiology, including information on population prevalence of genetic variants, gene-disease associations, gene-gene and gene- environment interactions, and evaluation of genetic tests.

HuGE Navigator has recently collaborated with Entrez Gene:

A link to HuGE Navigator has been added to the menu at the right side of the full report page in Entrez Gene. From HuGE Navigator, there is a link back to Entrez Gene. HuGE Navigator supplies Entrez Gene with the PubMed identifiers for citations HuGE Navigator staff curated for human genes.

For more information about HuGE Navigator, see this recently published paper:

A Navigator for Human Genome Epidemiology Nat Genet 40, 124 - 125 (2008) by Wei Yu, Marta Gwinn, Melinda Clyne, Ajay Yesupriya & Muin J Khoury