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Approach to the patient with a suspected drug eruption.

Semin Cutan Med Surg. 2007 Sep;26(3):147-54

Authors: Cotliar J

Diagnosis and management of adverse drug reactions constitutes a significant portion of U.S. health care costs. The clinical presentation of these reactions varies from self-limited, morbilliform drug eruptions to more severe, systemic reactions, such as drug hypersensitivity syndromes, Stevens-Johnson syndrome, and toxic epidermal necrolysis, which are associated with significant mortality. The role of the consulting dermatologist is to expeditiously and effectively recognize and classify these drug reactions on the basis of patient histories and awareness of the dermatologic literature as it pertains to the rates of and risk factors for adverse cutaneous events associated with use of numerous medications. This combined with a systematic approach to the workup of a patient with a suspected drug eruption allows for prompt recognition, classification and treatment of these unforeseen events.

PMID: 18070681 [PubMed - indexed for MEDLINE]

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Related Articles

Approach to the patient with presumed cellulitis.

Semin Cutan Med Surg. 2007 Sep;26(3):168-78

Authors: Kroshinsky D, Grossman ME, Fox LP

Dermatologists frequently are consulted in the evaluation and management of the patient with cellulitic-appearing skin. For routine cellulitis, the clinical presentation and patient symptoms are usually sufficient for an accurate diagnosis. However, when the clinical presentation is somewhat atypical, or if the patient fails to respond to appropriate therapy for cellulitis because of routine bacterial pathogens, the differential diagnosis should be rapidly expanded. We discuss the approach to the patient with presumed cellulitis, with an emphasis on the differential diagnosis of cellulitis in both the immunocompetent and immunucompromised patient.

PMID: 18070684 [PubMed - indexed for MEDLINE]

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