Emergence of oseltamivir-resistant influenza A H1N1 virus during the 2007-2008 winter season in Luxembourg: clinical characteristics and epidemiology.

Antiviral Res. 2009 Oct;84(1):91-4

Authors: Mossong J, Opp M, Gerloff N, Hau P, Kremer J, Lackenby A, Gregory V, Even J, Huberty-Krau P, Muller CP, Schneider F

Human cases of oseltamivir-resistant influenza A H1N1 virus emerging in 2007-2008 in Luxembourg were not associated with treatment, prophylaxis or stockpiling of oseltamivir. Following initial local seeding, oseltamivir-resistant strains spread synchronously to sensitive strains causing a similar epidemiology and clinical symptoms.

PMID: 19665488 [PubMed - indexed for MEDLINE]