Mar 312010
 

U.S. Trends in Hospitalization and Generalist Physician Workforce and the Emergence of Hospitalists.

J Gen Intern Med. 2010 Mar 30;

Authors: Meltzer DO, Chung JW

BACKGROUND: General internists and other generalist physicians have traditionally cared for their patients during both ambulatory visits and hospitalizations. It has been suggested that the expansion of hospitalists since the mid-1990s has "crowded out" generalists from inpatient care. However, it is also possible that declining hospital utilization relative to the size of the generalist workforce reduced the incentives for generalists to continue providing hospital care. OBJECTIVE: To examine trends in hospital utilization and the generalist workforce before and after the emergence of hospitalists in the U.S. and to investigate factors contributing to these trends. DESIGN: Using data from 1980-2005 on inpatient visits from the National Hospital Discharge Survey, and physician manpower data from the American Medical Association, we identified national trends before and after the emergence of hospitalists in the annual number of inpatient encounters relative to the number of generalists. RESULTS: Inpatient encounters relative to the number of generalists declined steadily before the emergence of hospitalists. Declines in inpatient encounters relative to the number of generalists were driven primarily by reduced hospital length of stay and increased numbers of generalists. CONCLUSIONS: Hospital utilization relative to generalist workforce declined before the emergence of hospitalists, largely due to declining length of stay and rising generalist workforce. This likely weakened generalist incentives to provide hospital care. Models of care that seek to preserve dual-setting generalist care spanning ambulatory and inpatient settings are most likely to be viable if they focus on patients at high risk of hospitalization.

PMID: 20352367 [PubMed - as supplied by publisher]

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Mar 302010
 
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Is there still a role for peripheral parenteral nutrition?

Nutr Clin Pract. 2009 Dec;24(6):709-17

Authors: Gura KM

Peripheral parenteral nutrition (PPN) is often viewed as the stepchild of parenteral nutrition (PN) infused via a central venous catheter. Anecdotal reports suggest that there has been increased interest in PPN in the United States and even more so in Europe because of improvements in catheter design and infusion technology, both of which have the potential to decrease complications such as infusion phlebitis. PPN, like PN via a central venous catheter, contains dextrose, amino acids, electrolytes, vitamins, and minerals, but in more limited capacity. One of the perceived benefits of PPN is the relative ease in establishing peripheral access, which may prevent delays in establishing nutrition support. PPN is intended for short-term use or supplementation. In most instances, it is used to maintain a previously well-nourished, nonhypermetabolic patient or to serve as a bridge to centrally administered infusions or enteral feedings until more suitable nutrition can be provided. In some cases, inappropriate use may result in infusion phlebitis or inadequate nutrient intake. Conflicting recommendations from various organizations further complicate and confuse prescribers. The intent of this review is to discuss PPN and the challenges its use presents to the practitioner.

PMID: 19955548 [PubMed - indexed for MEDLINE]

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Mar 302010
 
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The STRATIFY tool and clinical judgment were poor predictors of falling in an acute hospital setting.

J Clin Epidemiol. 2010 Jan;63(1):109-13

Authors: Webster J, Courtney M, Marsh N, Gale C, Abbott B, Mackenzie-Ross A, McRae P

OBJECTIVE: To compare the effectiveness of the STRATIFY falls tool with nurses' clinical judgments in predicting patient falls. STUDY DESIGN AND SETTING: A prospective cohort study was conducted among the inpatients of an acute tertiary hospital. Participants were patients over 65 years of age admitted to any hospital unit. Sensitivity, specificity, and positive predictive value (PPV) and negative predictive values (NPV) of the instrument and nurses' clinical judgments in predicting falls were calculated. RESULTS: Seven hundred and eighty-eight patients were screened and followed up during the study period. The fall prevalence was 9.2%. Of the 335 patients classified as being "at risk" for falling using the STRATIFY tool, 59 (17.6%) did sustain a fall (sensitivity=0.82, specificity=0.61, PPV=0.18, NPV=0.97). Nurses judged that 501 patients were at risk of falling and, of these, 60 (12.0%) fell (sensitivity=0.84, specificity=0.38, PPV=0.12, NPV=0.96). The STRATIFY tool correctly identified significantly more patients as either fallers or nonfallers than the nurses (P=0.027). CONCLUSION: Considering the poor specificity and high rates of false-positive results for both the STRATIFY tool and nurses' clinical judgments, we conclude that neither of these approaches are useful for screening of falls in acute hospital settings.

PMID: 19398296 [PubMed - indexed for MEDLINE]

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Mar 302010
 
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Transitions of Care Consensus Policy Statement American College of Physicians-Society of General Internal Medicine-Society of Hospital Medicine-American Geriatrics Society-American College of Emergency Physicians-Society of Academic Emergency Medicine.

J Gen Intern Med. 2009 Aug;24(8):971-6

Authors: Snow V, Beck D, Budnitz T, Miller DC, Potter J, Wears RL, Weiss KB, Williams MV, , , , , ,

The American College of Physicians (ACP), Society of Hospital Medicine (SHM), Society of General Internal Medicine (SGIM), American Geriatric Society (AGS), American College of Emergency Physicians (ACEP) and the Society for Academic Emergency Medicine (SAEM) developed consensus standards to address the quality gaps in the transitions between inpatient and outpatient settings. The following summarized principles were established: 1.) Accountability; 2) Communication; 3.) Timely interchange of information; 4.) Involvement of the patient and family member; 5.) Respect the hub of coordination of care; 6.) All patients and their family/caregivers should have a medical home or coordinating clinician; 7.) At every point of transitions the patient and/or their family/caregivers need to know who is responsible for their care at that point; 9.) National standards; and 10.) Standardized metrics related to these standards in order to lead to quality improvement and accountability. Based on these principles, standards describing necessary components for implementation were developed: coordinating clinicians, care plans/transition record, communication infrastructure, standard communication formats, transition responsibility, timeliness, community standards, and measurement.

PMID: 19343456 [PubMed - indexed for MEDLINE]

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Mar 302010
 
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Narrative Review: Should Teaching of the Respiratory Physical Examination Be Restricted Only to Signs with Proven Reliability and Validity?

J Gen Intern Med. 2010 Mar 27;

Authors: Benbassat J, Baumal R

OBJECTIVE: To review the reported reliability (reproducibility, inter-examiner agreement) and validity (sensitivity, specificity and likelihood ratios) of respiratory physical examination (PE) signs, and suggest an approach to teaching these signs to medical students. METHODS: Review of the literature. We searched Paper Chase between 1966 and June 2009 to identify and evaluate published studies on the diagnostic accuracy of respiratory PE signs. RESULTS: Most studies have reported low to fair reliability and sensitivity values. However, some studies have found high specificites for selected PE signs. None of the studies that we reviewed adhered to all of the STARD criteria for reporting diagnostic accuracy. CONCLUSIONS: Possible flaws in study designs may have led to underestimates of the observed diagnostic accuracy of respiratory PE signs. The reported poor reliabilities may have been due to differences in the PE skills of the participating examiners, while the sensitivities may have been confounded by variations in the severity of the diseases of the participating patients. IMPLICATION FOR PRACTICE AND MEDICAL EDUCATION: Pending the results of properly controlled studies, the reported poor reliability and sensitivity of most respiratory PE signs do not necessarily detract from their clinical utility. Therefore, we believe that a meticulously performed respiratory PE, which aims to explore a diagnostic hypothesis, as opposed to a PE that aims to detect a disease in an asymptomatic person, remains a cornerstone of clinical practice. We propose teaching the respiratory PE signs according to their importance, beginning with signs of life-threatening conditions and those that have been reported to have a high specificity, and ending with signs that are "nice to know," but are no longer employed because of the availability of more easily performed tests.

PMID: 20349154 [PubMed - as supplied by publisher]

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Mar 302010
 
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In vitro evaluation of ceftaroline alone and in combination with tobramycin against hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates.

Int J Antimicrob Agents. 2010 Mar 24;

Authors: Vidaillac C, Leonard SN, Rybak MJ

The aim of this study was to evaluate the in vitro activity of ceftaroline and its potential for synergy with tobramycin in comparison with vancomycin against a collection of hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA), including isolates with reduced susceptibility to glycopeptides. Ceftaroline, vancomycin, daptomycin and linezolid susceptibilities were determined for 200 HA-MRSA isolates. Four randomly selected strains [including one vancomycin-intermediate S. aureus (VISA) and one heteroresistant VISA (hVISA)] were evaluated in time-kill experiments with ceftaroline and vancomycin alone or combined with tobramycin at 0.25 and 0.5 times the minimum inhibitory concentration (MIC). MICs for 50% and 90% of the organisms (MIC(50) and MIC(90), respectively) were both 1mg/L for ceftaroline and were 1mg/L and 2mg/L, respectively, for vancomycin. The same ceftaroline MIC ranges (0.25-2mg/L) were observed for isolates recovered from respiratory tract samples, blood or skin. In time-kill experiments, no synergy was observed at 0.25x MIC against any tested isolates with either ceftaroline or vancomycin. In contrast, the combination of ceftaroline plus tobramycin at 0.5x MIC was synergistic against the two MRSA strains and the hVISA but was indifferent against the VISA isolate. In conclusion, ceftaroline demonstrated antimicrobial activity independently of the specimen source and exhibited lower MICs than vancomycin. Finally, at sub-MIC levels, ceftaroline plus tobramycin displayed significantly greater activity than vancomycin plus tobramycin against MRSA (P<0.01).

PMID: 20346632 [PubMed - as supplied by publisher]

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